Frankel has been installed as 8-11 favourite by Coral for the Dubai Dewhurst Stakes at Newmarket.
Henry Cecil's colt was a brilliant winner of the Royal Lodge Stakes at Ascot but could face his acid test at Headquarters.
His potential opponents include wide-margin Middle Park winner Dream Ahead (5-2) and Champagne Stakes winner Saamidd (5-1).
"We've seen some terrific performances from several two-year-old colts already this season, and if the market principals all turn up for the Dewhurst, it should be a mouthwatering showdown, with the winner certain to head into winter quarters as hot favourite for the 2,000 Guineas," said Coral's David Stevens.
"However, it is a measure of how highly we rate Frankel that Henry Cecil's charge is odds-on for the race, even though he could face fellow unbeaten Group winners such as Dream Ahead and Saamidd," added Stevens.
Dubai Dewhurst Stakes - Coral bet; 8-11 Frankel, 5-2 Dream Ahead, 5-1 Saamidd, 14-1 Dunboyne Express, Native Khan, 20-1 Seville, Titus Mills, 33-1 Roderic O'Connor, Strong Suit, 40-1 Elzaam, Glor Na Mara.